SAFC Pharma, Inc.
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Company Profile

SAFC Global focuses on custom-manufacturing, custom-packaging and customized raw-material supply services within Sigma-Aldrich. There are four divisions within SAFC, one of which is SAFC Pharma. Madison operates within this division. The Madison sites focus on the development and manufacture of small molecule active pharmaceutical ingredients. SAFC Madison is considered one of the premier high-potency development and manufacturing facilities in the world. The original site in the UW Research Park totals 62,000sf. It is FDA inspected and is one of a few facilities that have been certified by SafeBridge for potent compound handling. SAFC Madison maintains fully equipped R&D suites, kilolab and commercial pilot plant manufacturing capabilities. In April 2010, SAFC opened a second area facility in Verona. This $30M, 51,000sf manufacturing facility houses commercial scale reactors capable of producing HPAPI batch sizes up to 4,000 liters, which is up to 10 times greater than the capacity of the Madison site.
Business Sectors
Pharmaceuticals   Human Diagnostics  
Med or Lab Devices   Lab Reagents or Services  
Drug Manufacturing Food & Agribusiness  
CRO   Bioinformatics or Software  
    Other  
Company History
Tetrionics was founded in 1989 by Hector DeLuca and Peter Johnson to supply the pharmaceutical development market with high purity vitamin D analogs. One of its first clients was Abbott, for whom they manufacture paricalcitrol, the active pharmaceutical ingredient in Zemplar [this continues to the present time]. Its services have since been expanded to include synthesis and scale up, analytical chemistry, regulatory support and current good manufacturing practice (cGMP) production of active pharmaceutical ingredients across a broad range of structural classes of molecules with a strong emphasis on high potency and cytotoxic compounds. Sigma-Aldrich purchased Tetrionics in 2004 for $85 million and undertook a 38,000 sf expansion (to 62,000 sf total) that opened in 2006. In Aug08, SAFC announced plans to construct a $31 million 51,000sf GMP manufacturing facility at 1101 Kettle Moraine Trail in Verona to further increase capacity.

LEADERSHIP ROLL: Pete Johnson 1989-2004; Dennis Young 2004-2009; Dave Bormett 2009-2014; Patrick Kliptine 2014-present
SAFC Pharma, Inc.
Address 645 Science Drive
[Map] Madison
WI
53711
Phone 608-233-3115
Fax 608-233-6873
Website Link
Head Patrick Klipstine
Company Statistics
Global Headcount 155
Local Headcount 155
Year Founded 1990
Ownership Subsidiary
Stock Exchange

Parent Company
Divisional Level SAFC Global [St. Louis MO]
Senior Level Sigma-Aldrich Corp [St. Louis MO]
Global Headcount 7740
Website Link
Stock Exchange NASDAQ
Reference Documents
Corporate Profile
SAFC Pharma Madison Site Capabilities [View]
Virtual Video Tour [View]
News/Profiles
2010 - SAFC Manufacturing Facility to open in April [View]
2008 - SAFC Plans Verona GMP Manufacturing Facility [View]
1999 - Big Breakthrough for Tetrionics [View]
Reports
Sigma Aldrich 2009 Annual Report [View]
Sigma Aldrich 2008 Annual Report [View]
Selected Press Releases
2010 - SAFC Opens $30M Verona Manufacturing Facility [View]
2006 - SAFC Doubles Production Space [View]
2004 - Sigma Aldrich Buys Tetrionics [View]