Arrowhead Madison Inc.


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Company Profile

Arrowhead Madison, the research center for Arrowhead Pharmaceuticals, Inc., is a discovery research center of excellence for RNAi delivery. RNA Interference, or gene silencing, is a natual cellular mechanism that regulates gene expression and protein production.

The Madison research unit does not have its own website.
Business Sectors
Pharmaceuticals Human Diagnostics  
Med or Lab Devices   Lab Reagents or Services  
Drug Manufacturing   Food & Agribusiness  
CRO   Bioinformatics or Software  
Company History
Mirus Corporation was founded in 1995 by Drs. Jon A Wolff, James Hagstrom and Vladimir Budker, and changed its name to Mirus Bio Corporation in 2004. Mirus Bio's lead therapeutic programs were RNAi therapies based on its proprietary Dynamic PolyConjugates™ siRNA delivery platform and gene therapies utilizing its Pathway IV ™ delivery protocol. The discovery of Dynamic PolyConjugates led to the acquisition of the company by Hoffmann-La Roche in 2008 for $125 million. Concurrent with the acquisition, Roche divested the research tools division to a newly formed company, Mirus Bio LLC. In October 2011, Arrowhead Research Corporation of Pasadena CA purchased Roche Madison Inc. and acquired other RNAi IP rights owned by Roche, renaming the company Arrowhead Madison. Arrowhead changed its name to Arrowhead Pharmaceuticals, Inc. in 2016.

LEADERSHIP ROLL: Terry Sivesind 1996-2003; Russell R Smestad 2003-2008; Jon Wolff MD & Jim Hagstrom PhD 2008-2010; David Lewis PhD 2011-2016
Arrowhead Madison Inc.
Address 502 South Rosa Road
[Map] Madison
Phone 608-316-3890
Fax 608-441-0741
Website Link
Head Bruce Givens
Company Statistics
Global Headcount 110
Local Headcount 90
Year Founded 1995
Ownership Subsidiary
Stock Exchange

Parent Company
Divisional Level
Senior Level Arrowhead Pharmaceuticals, Inc. [Pasadena, CA]
Global Headcount
Website Link
Stock Exchange NASDAQ
Reference Documents
Corporate Profile
Dynamic PolyConjugates Technology Profile [View]
2018 - Arrowhead Earns $10M from Amgen [View]
2017 - Arrowhead Eyeing Comeback [View]
2016 - Arrowhead Madison Profile with D Lewis [View]
2008 - Roche Buys Mirus Bio Corp for $125 Million [View]
Selected Press Releases
2016 - Arrowhead Refocuses Research [View]
2011 - Arrowhead Appoints VPs Lewis and Rozema [View]
2011 - Arrowhead Research Corp Acquires Roche Madison [View]
2008 - Roche to Acquire Mirus Bio Corp July 22 2008 [View]
Pfizer-Mirus RNAi Discovery Collaboration Jan 2007 [View]